Now Reading: I. RESVERATROL AND ITS ROLE IN CARDIOVASCULAR, CHRONIC DISEASES AND ANTI-INFLAMMATORY ACTIVITY

I. RESVERATROL AND ITS ROLE IN CARDIOVASCULAR, CHRONIC DISEASES AND ANTI-INFLAMMATORY ACTIVITY

Tomé-Carneiro J., Gonzálvez M., Larrosa M., Yáñez-Gascón M.J., García-Almagro F.J., Ruiz-Ros J.A., Tomás-Barberán F.A., García-Conesa M.T., Espín J.C. Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in peripheral blood mononuclear cells: A triple-blind, placebo-controlled, one-year clinical trial in patients with stable coronary artery disease. Cardiovasc. Drugs Ther. 2013;27:37–48.
https://pubmed.ncbi.nlm.nih.gov/23224687/

Lee SJ, Choi SK and Seo JS, Grape skin improves antioxidant capacity in rats fed a high fat diet. Nutr Res Pract 3:279–285 (2009). https://pubmed.ncbi.nlm.nih.gov/20098580/

Rahman I., Biswas S.K., Kirkham P.A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem. Pharmacol. 2006;72:1439–1452. https://pubmed.ncbi.nlm.nih.gov/16920072/

Agarwal B., Campen M.J., Channell M.M., Wherry S.J., Varamini B., Davis J.G., Baur J.A., Smoliga J.M. Resveratrol for primary prevention of atherosclerosis: Clinical trial evidence for improved gene expression in vascular endothelium. Int. J. Cardiol. 2012;8:9–11.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646959/

Borriello A., Cucciolla V., Della Ragione F., Galletti P. Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis. Nutr. Metab. Cardiovasc. Dis. 2010;20:618–625.
https://pubmed.ncbi.nlm.nih.gov/20850033/

Cao Z., Li Y. Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: Protection against oxidative and electrophilic injury. Eur. J. Pharmacol. 2004;489:39–48.
https://pubmed.ncbi.nlm.nih.gov/15063153/

Ungvari Z., Bagi Z., Feher A., Recchia F.A., Sonntag W.E., Pearson K., de Cabo R., Csiszar A. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am. J. Physiol. Heart Circ. Physiol. 2010;299:H18–H24.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904129/

Baur J.A., Sinclair D.A. Therapeutic potential of resveratrol: The in vivo evidence. Nat. Rev. Drug Dis. 2006;5:493–506.
https://pubmed.ncbi.nlm.nih.gov/16732220/

Csiszar A. Anti-inflammatory effects of resveratrol: Possible role in prevention of age-related cardiovascular disease. Ann. N. Y. Acad. Sci. 2011;1215:117–122.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058481/